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The 12 Best Puppy Milk Replacers

Newborn puppies are the cutest little creatures on the earth. When a dog gives birth, it is an exciting time, and seeing the puppies suckle is a special moment between the mother and her litter. Occasionally, a puppy may be rejected or abandoned by its mother, or the mother may not produce milk or be ill. If this occurs, the newborn puppy will require human assistance to ensure a healthy start to life.

This is where puppy milk substitutes come into play. It is essential to deliver essential nutrients, and many milk substitutes closely resemble breast milk, which is what you desire. In this article, BestForPets (bestforpets.org) will discuss the best puppy milk replacers to assist you in making an informed selection for your new dog.


PetAg Esbilac Liquid Milk Supplement

PetAg Esbilac Liquid Milk Supplement provides a full, nutritionally-balanced, and easily digested feeding supply for pups. This formulation can also be used as a supplement for nursing puppies and stressed adult dogs in need of a nutritional boost. This formula contains the essential vitamins, minerals, and amino acids for a good start for pups.

Since this recipe is in liquid form, no mixing is required. Simply open the package and follow the suggested serving sizes. The liquid recipe has a short shelf life after opening, which is a downside, but the good news is that this product comes in an 11-ounce can at a wonderful price. Unopened cans can be stored in a cold, dry location for up to six weeks, but opened cans should be consumed within three days.

On occasion, cans may come damaged, in which case you may contact the manufacturer. In spite of this, PetAG is a reputable name in the market with over 70 years of experience. With its low pricing and essential vitamins, minerals, and amino acids, we consider this product to be the greatest puppy milk replacer overall.


  • Extremely appetizing and digestible
  • Contains identical vitamins, minerals, and amino acids as breast milk.
  • Adult dogs can also utilize
  • Reasonable in cost
  • Unopened cans have a six-week shelf life.


  • Can arrive dented
  • Opened cans have a 72-hour shelf life.


Hartz Powdered Milk Replacer Formula

Hartz Powdered Milk Replacer Formula may be a suitable alternative if you’re looking for a powdered formula. This product comes in a 12-ounce container and is created with genuine milk to mimic breast milk precisely.

You may feel confident that the pups will receive all of the important nutrients, including protein for optimal growth, calcium for strong bones, magnesium for muscle and heart health, vitamin A for eye development, linoleic acid for healthy skin and coat, antioxidants, and omegas.

Not only is this formula meant to mimic breast milk, but it is also excellent for pregnant or nursing mothers, as well as the elderly who want a nutritional boost. It is simple to digest and blend, however mixing at room temperature yields the greatest results.

We believe this product is the most cost-effective puppy milk replacer due to its nutritional advantages for pups, pregnant or nursing moms, and older citizens.

This product contains BHA and BHT, which are anti-oxidants that slow down the oxidation process and must be mentioned. These preservatives are a contentious substance.


  • Formula meant to resemble breast milk
  • Contains calcium, magnesium, and vitamin A
  • Linoleic acid for skin and coat health
  • Appropriate for pregnant or nursing moms as well as retirees
  • Affordable


  • Includes BHA and BHT


Royal Canin Babydog Puppy Milk

Royal Canin Babydog Puppy Milk is an appropriate milk substitute for puppies up to two months of age. It is made to closely resemble breast milk and comes with a feeding kit. This easy-to-feed recipe is enriched with DHA omega fatty acids for brain development and may be sprinkled on dry food to provide older dogs with a nutritional boost.

Royal Canin is a reputable brand within the pet business, producing products with the necessary proteins, vitamins, minerals, and healthy fats for maximum health.

It mixes well and is easily digestible. The only disadvantage we can identify is that it is somewhat pricey.


  • DHA content in infant formula is comparable to that of breast milk.
  • Appropriate for elders
  • Includes a feeding kit


  • Expensive


PetAg Goat’s Milk Esbilac Powder Milk Supplement

If you enjoy PetAG’s goods, then the PetAg Goat’s Milk Esbilac Powder Milk Supplement might be what you’re searching for. This formulation is comprised of genuine goat’s milk and has no hazardous preservatives.

It includes vitamin A, vitamin B12, vitamin E, vitamin D3, magnesium, and calcium. It is readily digested and contains prebiotics and probiotics to ensure that your pups receive the essential nutrition for growth.

This product must be refrigerated for up to 24 hours, and powder that has been opened must be refrigerated for three months. This product can also be frozen for up to six months.

This product is costly and may not mix properly with water, resulting in a slightly lumpy consistency.


  • Made from natural goat’s milk
  • Contains no preservatives
  • Simple digestion
  • Long storage life
  • Can be frozen for six months


  • Expensive
  • After adding water, the formula may be lumpy.


Dogzymes Puppy-Bac Milk Replacer

Dogzymes Puppy-Bac Milk Replacer is specially created to include the same proportions of protein, lipids, and nutrients as mother’s milk. This milk substitute can be provided to the mother if she needs an increase in milk production.

The producer added coconut oil and whey and milk for protein. It contains all the necessary vitamins and minerals and probiotics to guarantee that the puppies absorb them. Additionally, the product has no artificial preservatives.

This product has a shelf life of one year and is simple to combine. The 8-ounce pack, 1-pound pack, 2-pound pack, and 4-pound pack are all available at a fair price. Senior dogs in need of a little additional food can also benefit from the formula, which is well-tolerated by newborn pups with no gastrointestinal difficulties.

Some puppies may not enjoy the flavor, and feeding them may need patience.


  • Like mother’s milk
  • Coconut oil for more fat
  • Contains probiotics
  • Free of synthetic preservatives
  • Suitable for older dogs
  • 12-month shelf life


  • Some puppies might not enjoy the flavor


PetAg PetLac Powder Milk Supplement

PetAg’s PetLac Powder Milk Supplement is another excellent product. This formula is appropriate for puppies up to six weeks of age, including newborns.

In addition to probiotics, it provides all the vitamins and minerals required for healthy growth and development. It also contains cow’s milk and vegetable protein as a source of energy for the puppies. It may be refrigerated for up to 14 days once it has been opened and comes in a 10.5-ounce jar.

Occasionally, the product may arrive partially filled and is non-returnable. The powder may clump when stirred, however shaking the container before to mixing assists in dissolving the powder.


  • Contains probiotics
  • Can be stored in the refrigerator for 14 days after opening.
  • Includes all essential vitamins and minerals


  • The product may come partially full.
  • The powder may form clumps when mixing.


Nutri-Vet Powder Milk Supplement

Nutri-Vet Powder Milk Supplement contains probiotics derived from its own natural formula, Opti-Gut, which helps in growth and development.

It includes whey protein to provide additional amino acids that support healthy muscles, skin, and other tissues. Additionally, pregnant or nursing moms and older dogs can utilize this formula. This recipe was developed by veterinarians and is prepared in the United States.

The product may arrive unopened and includes the preservatives BHA and BHT. It could not mix well and leave a grainy residue.


  • Opti-Gut formula for probiotics
  • Veterinarian-formulated
  • Made in the United States of America


  • Includes BHA and BHT
  • The product may arrive open
  • Might not mix nicely
  • Possibly leaves a grainy residue.


PetNC Natural Care Milk Replacer

PetNC Natural Care Milk Replacer is a powdered milk substitute containing colostrum, a fluid generated by the mother’s mammary glands that offer essential nutrients and aids in the development of the immune system. Formulated by a veterinarian using human-grade components for optimal nourishment.

This formula is suitable for newborns and puppies up to 6 weeks of age and is loaded with proteins, lipids, and carbs to ensure a healthy start. If you have newborn kittens, it is also appropriate for them! Pregnant and nursing mothers can also benefit from this formula.


  • Contains colostrum
  • Also suitable for newborn kittens
  • Appropriate for pregnant and nursing mother dogs
  • Human-grade components


  • Includes BHA and BHT


Vets Preferred Advanced Milk Rx Dog Supplement

Vets Preferred Advanced Milk Rx Dog Supplement is an easily digestible powdered supplement for newborn puppies. It is created from natural milk fortified with colostrum to offer all the necessary vitamins, minerals, proteins, and lipids for a healthy beginning.

Digestive enzymes complete the formulation to support healthy digestion and immunity. Pregnant women, nursing mothers, and older citizens can also benefit from the antibodies in this veterinarian-formulated formula.

The powder may have a grainy texture, and the mixing directions may be more specific. Some pups and adult dogs may get diarrhea. Stop providing the product immediately and visit your veterinarian if this occurs.

All Vets products are manufactured in a GMP-certified facility to ensure quality and safety, and they come in 12-ounce jars.


  • Contains colostrum
  • Appropriate for pregnant or nursing moms and older citizens
  • Designed by veterinarians
  • Using only natural milk
  • Produced in a facility with GMP certification


  • The powder may be grainy upon mixing.
  • Faulty directions
  • Possibly causes diarrhea in certain puppies.


Tailspring Milk Replacer

The 16-ounce packet of Tailspring Milk Replacer is manufactured from entire goat’s milk. Goat’s milk is ideal for young puppies since it is easier on their delicate stomachs. It does not include any artificial flavors, colors, or preservatives, but it does have an abundance of components that are 100% human-grade.

This formulation is rich in vitamins, calcium, magnesium, and taurine to promote a healthy heart, healthy eyes, and a healthy gastrointestinal tract. It is particularly made to mimic breast milk, and the producer has been a reputable brand since 1934.

Once opened, it may be refrigerated for up to three months and used as a meal topper or a special treat for adult dogs. This product is more expensive than others on the market, but the clean components justify the additional cost.


  • Natural and unadulterated ingredients
  • Produced with entire goat’s milk
  • Includes taurine
  • Can be used as a topping for adult dogs’ meals.


  • Expensive

Buyer's Guide

It may be both satisfying and terrifying to care for newborn pups whose mother has rejected them or died. Selecting the greatest puppy milk replacers will guarantee that the lovely puppies have the healthiest possible start to life.

Now that we’ve discussed our top recommendations for the finest puppy milk replacer, let’s review what to look for in a product.


Newborn pups are vulnerable and require optimal nourishment immediately after birth. Since they are not receiving their mother’s milk, it is essential to feed them with the most natural, preservative-free formula available.

The mother’s natural milk contains no preservatives, thus there is no need to give the infants any form of preservative. Several of the above-listed goods include the chemical antioxidants BHA and BHT. Although the FDA has allowed these preservatives for human consumption, many individuals continue to be wary.


Fantastic if the formula contains colostrum, a source of nutrition and immunoglobulins! During the first two days after birth, the mother’s mammary glands produce colostrum spontaneously. Colostrum is essential for the survival of pups in their first few days of life.

The majority of the puppy milk replacements we evaluated contain colostrum, and we strongly advise selecting a product containing this important, life-saving vitamin.

Duration of shelf life

Powdered formulations have a longer shelf life than their liquid counterparts, and the majority of consumers believe powdered formulations to be more cost-effective. However, be careful to read the directions before purchasing to avoid wasting a lot of the product, since some of them may only be refrigerated for 24 hours after opening.

Essential Fatty Acids

Omega-3 fatty acids, commonly known as DHA, are essential for brain and eye development, so be sure to read the label for this key ingredient.


It might be annoying when a product does not combine well. Occasionally, the powder will clump and sink to the bottom before you have the opportunity to feed it. In our product reviews, we attempt to make you aware of this information. However, do not give up, since sometimes all that is required is patience.

Prebiotics as well as Probiotics

Prebiotics and probiotics facilitate digestion in puppies. Prebiotics provide fiber to stimulate the growth of beneficial bacteria in the colon, whereas probiotics are healthy gut bacteria that aid in illness prevention. It also strengthens the immune system and aids in the battle against hazardous germs. We strongly suggest obtaining a formula containing these ingredients.

Minerals and vitamins

To get off to a healthy start, puppies require a large number of calories and protein. Also, be on the lookout for vitamins and amino acids.


We propose PetAg Esbilac Liquid Milk Supplement as the finest puppy milk substitute overall. It is economically priced, has a long shelf life, and provides the essential vitamins, minerals, and amino acids to maintain maximum health. Hartz Powdered Milk Replacer Formula resembles mother’s milk and contains linoleic acid for a healthy coat and skin, all at an affordable price. It is vitally crucial to monitor the growth and weight increase of hand-reared puppies, as no artificial milk can equal the nutritional value of a mother’s milk.

BestForPets (bestforpets.org) hope that our evaluations of the best puppy milk replacers will make your decision easier. Your product search should go more smoothly now that you know what to look for.

Author Image

Dr. Deborah Fletcher

Deborah R. Fletcher, DVM, is a skilled veterinarian with more than 15 years of experience dealing with companion and exotic animals. She has experience caring for a variety of animals, including household cats and dogs, reptiles, birds of prey, and even primates. Dr. Fletcher is a valuable part of the BestForPets team, where she contributes to their aim of providing pets and their owners with the finest possible treatment and services.

Veterinarian (DVM) Dr. Deborah Fletcher


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