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The 11 Best Cleaners For Dog Urine

The discovery of a urine stain on a hardwood floor can be a vexing experience for dog owners who are having trouble with indoor accidents from their pets.

It is an acknowledged fact that accidents will happen since pets cannot be under constant observation. Previous attempts with pet cleansers may have been futile. What now?

If you're still looking for a good dog urine cleaner, you're in the right place. In this article, BestForPets (bestforpets.org) will discuss our top selections for the best cleaners for dog urine.

We'll go over each option and let you know our thoughts so you can make the best decision for your needs.

icon Vet Approved
icon Reviewed & Fact - Checked by

Deborah R. Fletcher (DVM)


The information provided is current and up-to-date, in line with the latest research conducted in the field of veterinary medicine.

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Hepper Advanced Bioenzyme Pet Stain & Odor Eliminator Spray – Overall Winner

Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with carpet, hardwood, tile, and fabric

The Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray is a potent cleansing solution designed for cleaning dog urine on hardwood floors.

This bio-enzyme formulation binds, lifts, and eliminates even the most stubborn stains and persistent odors, leaving your home smelling fresh and clean.

This product is highly effective in removing a range of pet messes, such as urination, excrement, vomit, and saliva, from different surfaces like carpets, floors, furniture, and clothing.

The advanced enzymatic cleansing technology of Hepper’s spray allows it to penetrate deeply into the molecular structure of stains and odors, dissolving them at their source and carrying them away.

Unlike many other pet odor eliminators on the market, Hepper’s does not rely on harsh or foul chemical fragrances to mask odors. Instead, it completely eliminates them, leaving behind a fresh, natural scent.

After mixing the bottle and applying the spray to the affected area, you should wait for the formula to take effect.

The formula should be left to set for at least one hour, but preferably longer, to ensure that all stains and odors are fully eliminated.

Hepper’s Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray is an excellent option for pet owners seeking a potent, effective, and user-friendly cleaning product.

It is our top recommendation for pet stain and odor removal due to its advanced enzymatic technology, natural fragrance, as well as its effectiveness on a variety of surfaces and accidents.


Effective on pee, feces, and more


Eliminates odors

Bio-enzyme formula


Requiring time to set

OUT! Oxy Fast Pet Stain & Odor Remover – Top Pick

OUT! Oxygen Activated Pet Stain & Odor Remover 32oz

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hard surfaces, carpet, bedding, furniture, and washing

OUT! Oxy Fast Activated Pet Stain & Odor Remover is a specialized cleaning solution that effectively eliminates dog urine, regurgitation, excrement, and blood stains from a variety of surfaces, including carpets.

This product is available at an attractive price in a 32-ounce spray container, which makes it a cost-effective option for pet owners.

The oxy cleaning power of this solution allows it to penetrate deeply into the core of stains and remove them from the surface.

This formula is designed to combat stains and odors at their source, ensuring that they are removed permanently and never return.

In addition, this detergent is safe to use around dogs and children, making it an attractive option for households with pets and young children. It can also be used as a pre-treatment and is compatible with all water-safe surfaces.

While multiple treatments may be required to entirely eliminate stubborn stains, OUT! Oxy Fast Activated Pet Stain & Odor Remover continues to be one of the most effective and reasonably priced cleaners for dog urine on hardwood floors.

Its adaptability and oxygen-releasing formula make it ideal for removing various stains and odors, including those caused by urine, vomit, excrement, blood, soil, grass, juice, coffee, tea, infant formula, spaghetti sauce, and other substances.

In conclusion, pet owners can rely on OUT! Oxy Fast Activated Pet Stain & Odor Remover as a dependable and effective cleaning product to rid their residences of pet-related stains and odors.


Blood, urine, feces, and vomit are eliminated

Oxygen cleaning ability

Safe for use around children and pets

Reasonable pricing


May require multiple treatments to remove stain

TriNova Pet Stain & Odor Remover – The Superior Option

TriNova Natural Pet Stain and Odor Remover Eliminator

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hard surfaces, upholstery, carpeting, and furniture

TriNova Pet Stain & Odor Remover is a safe and all-natural cleaning product for pet owners.

This cleaner effectively removes pet-related stains and odors, such as regurgitation, excrement, and saliva, because it contains bio-enzymes derived from plants.

This chemical-free cleaner is suitable for use on various surfaces, including carpets, upholstery, and furniture.

TriNova Pet Stain & Odor Remover is non-toxic and safe to use around children and pets because of its natural constituents.

Notably, this cleaner has a strong fragrance, which can be overpowering for some individuals. However, the all-natural ingredients and professional potency justify the higher price compared to other available cleaners.

TriNova Pet Stain & Odor Remover is available in 32-ounce aerosol and gallon containers, giving pet owners multiple options.

It can be used on various surfaces, including linens, mattresses, cages, kennels, laundry, clothes, hardwood, litter boxes, and even tiny animal cages, due to its versatility.

TriNova Pet Stain & Odor Remover is an effective and environmentally friendly cleaning product that pet owners can rely on. Its natural ingredients and professional potency make it a top choice for pet stain and odor removal.

In addition, the 100% satisfaction guarantee ensures that pet owners can purchase with confidence.


100% pure components

Removes saliva, vomit, and feces

Safe with children and animals


Strong perfume smell


The Simple Green Bio Stain & Odor Remover for Dogs

Bio Active Stain & Odor Remover for Pet & Carpet

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hardwood flooring, hard surfaces, and carpet

Simple Green Bio Dog Stain & Odor Remover is an efficient cleaning product that utilizes enzymes and beneficial microbes to eliminate a wide range of pet-related stains, such as urine, excrement, vomit, and more.

This biologically derived solution breaks down stains with enzymes, which are then digested by beneficial bacteria. The result is a surface that is free of stains and odors, as the unpleasant smell has been completely eliminated.

Simple Green Bio Dog Stain & Odor Remover is suitable for use on a variety of surfaces, such as hardwood floors, finished wood, tile, laminate, vinyl, concrete, and upholstery.

It is available at a reasonable price in 32-ounce bottles and 1-gallon containers. When dealing with older stains, it may be necessary to apply the solution multiple times to achieve optimal results.

This non-toxic formula effectively eliminates new and old stains without harming pets. It also discourages repeat visits and comments, ensuring that the issue is completely resolved.

Simple Green Bio Dog Stain & Odor Remover is a versatile solution for pet owners, as it can be used to sanitize carpets, fabric, and upholstery.

Additionally, it has never been subjected to animal testing, ensuring that it is an ethical and humane product.

Pet owners can rely on Simple Green Bio Dog Stain & Odor Remover to eliminate a wide range of pet-related stains and odors because it is both effective and affordable.

Its non-toxic composition, efficacy, and adaptability make it an excellent option for pet owners seeking a dependable and safe cleaning solution.


Biologically-based remedy

Leaves a pleasant aroma

Removes all widespread pet stains



May require multiple applications to be effective

The Hard Floor Stain & Odor Remover by Nature’s Miracle

Nature's Miracle Hard Floor Cleaner, Dual-Action Stain & Odor Remover

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hard surfaces and flooring

Nature's Miracle Dual Action Hard Floor Stain & Odor Remover is a powerful cleanser for removing dog urine stains from hardwood floors.

It is suitable for use on all sealed hard surfaces and hardwood floors because it contains bio-enzymatic agents that break down even the most persistent stains.

Not only does this product eliminate dog urine stains, but it also eliminates unpleasant odors. It does not require washing, which simplifies the cleaning procedure. Furthermore, it can eliminate feces, vomit, and other organic substances.

This product is suitable for use on sealed wood, vinyl, linoleum, ceramic tiles, brick, concrete, and grout, and its 24-ounce spray bottles are reasonably priced.

When cleaning flooring surfaces, it is essential to check if they are sealed or unfinished and choose a product accordingly to avoid any potential damage.

Nature’s Miracle Hard Floor Cleaner is an effective liquid stain and odor remover for urine, feces, grease, and oil. On sealed wood, linoleum, vinyl, concrete, and ceramic tile, it effectively eliminates new and ingrained stains and odors.

The bio-enzymatic formula thoroughly cleans and protects the floor’s natural finish. This product is safe for pets and household use, and pet owners have favored it for over 35 years.

When properly used, it is safe for use around pets. The manufacturer stands behind this product and is committed to resolving any concerns you may have.

Nature’s Miracle Dual Action Hard Floor Stain & Odor Remover is a highly recommended product for pet owners seeking to eliminate dog urine stains and odors from hardwood floors.


Includes bio-enzyme agents

Eliminates spots and smells

No rinsing necessary



Some may find odors overwhelming

Cannot be used on unfinished or unsealed floors

Four Paws Wee-Wee Stain and Odor Remover

Four Paws Wee-Wee Pet Stain & Odor Eliminator for Urine

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hardwood and carpet

The Advanced Four Paws Wee-Wee Formulation Dog Stain & Odor Eliminator is a non-toxic, clinically formulated product that effectively eliminates dog urine stains and odors, as well as other common pet stains such as vomit, feces, and blood.

This pet stain and odor remover is safe for use on a variety of surfaces, including hardwood floors, carpets, tiles, and furniture.

It also prevents canines from returning to the same area to defecate. However, it is essential to test for colorfastness on a concealed area before use to prevent unwanted damage.

In addition to eliminating urine stains and odors, this product also protects treated surfaces and prevents resoiling.

It is an effective cleaner for carpets, floors, furniture, and linens. This pet stain and odor remover is safe for use in both pet and residential settings.

The product is available in both 32-ounce and 64-ounce bottles, and it comes with a money-back guarantee if you are not satisfied with its performance.


Non-toxic remedy

Eliminates all typical pet stains and odors

Safe for many surfaces


None as far as we can see

The Best Pet Products for Emmy Enzyme Pet Odor & Stain Eraser

EBPP Odor & Stain Eraser - Made in The USA

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hard surfaces, carpet and fabric

The Best Pet Products for Emmy Enzyme-Based Pet Odor & Stain Eraser has a triple-action formula that removes stains, neutralizes odors, and prevents pheromone-induced soiling.

This innovative product contains active enzymes that quickly begin digesting odors and stains caused by urine, excrement, and other organic substances.

Unlike other products that merely mask odors, this solution penetrates the source of the stain and discourages pets from repeatedly soiling the same area.

This American-made product has a delightful lavender scent that eliminates unpleasant odors without leaving a chemical aftertaste. Lavender has a calming effect on both pets and their owners.

Our pet odor and stain enzyme cleaner is the most effective dog and cat urine detergent on the market, guaranteed to receive 4.5 out of 5 stars from satisfied pet owners.

At Emmy’s Best Pet Products, we take pride in providing results without the use of gimmicks or empty promises. Our product is effective, and we guarantee your satisfaction.

Our refund policy allows for a full refund, even if the container is empty, if you are unsatisfied with the results. With our 100% Paws Promise Manufacturer’s Guarantee, you have nothing to lose.

This versatile product can be used on most surfaces, including kennels, carriers, and even laundry. However, it may not be effective in eliminating long-standing and stubborn discoloration.

Therefore, it is recommended to use this product as soon as possible after a stain occurs.

The Best Pet Products for Emmy Enzyme-Based Pet Odor & Stain Eraser is a safe, effective, and pleasantly scented solution for pet owners looking to eliminate pet-related odors and stains.

You can trust us to provide you and your furry companions with satisfying results.


Made in the United States of America

Contains enzymes capable of penetrating stains

Safe for many surfaces


The aroma of lavender may be too overpowering for certain people

Not likely to erase old stains

Simple Green Oxy Stain & Odor Oxidizer for Dogs

Oxy Dog Stain & Odor Oxidizer – Peroxide Cleaner for Urine

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hard surfaces, hardwood flooring, and carpet

The color-safe formula of Simple Green Oxy Dog Stain & Odor Oxidizer uses the natural power of peroxide to oxidize organic soils, providing a permanent solution for stains and odors.

This product is pet-friendly and effective on all pet-related stains, including urine, excrement, scent markings, blood, and vomit.

This stain and odor oxidizer can be used on a variety of surfaces, including concrete, carpet, finished wood, linoleum, and fabrics.

It leaves a pleasant scent, eliminating the need to tolerate harsh chemical aromas. Additionally, this formulation is suitable for use on pet containers and bedding.

Some satisfied customers have reported that this formula is more effective at eliminating odors than older products.

The product is available in both 32-ounce bottles and gallon-sized containers, providing consumers with a range of options to choose from.

Consumers can trust that this product aligns with ethical standards in the pet industry due to its commitment to not performing animal testing.

Overall, Simple Green Oxy Dog Stain & Odor Oxidizer is a safe, effective, and ethical solution for pet-related stains and odors.


For oxidation, a peroxide solution is used

Clean, fresh fragrance

Safe for many surfaces


Does not effectively remove existing stains

OdoBan Neutral pH No-Rinse Floor Cleaner

OdoBan Professional Series Neutral pH No Rinse Floor Cleaner Concentrate, 1 Gallon

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  • Yes, stain remover
  • Odor Remover: Yes
  • Safe for: varnished wood, vinyl, laminate, and glazed tile

The OdoBan No-Rinse Neutral pH Floor Cleaner is a highly effective cleaning solution that eliminates stubborn stains with its neutral pH, no-rinse formula.

This non-toxic product is suitable for use on hard surfaces, in hard floor cleaning equipment, and on treated wood. It is ideal for removing numerous pet stains and will not harm surface finishes.

Dilution is recommended for optimal results, as the solution may leave a residue. It is important to avoid using the solution on carpets to prevent damage.

This floor cleaner is available in both 32-ounce bottles and 1-gallon containers and has a refreshing citrus fragrance.

Its naturally derived surfactant system effectively cleans all concrete floors and surfaces without the use of potentially hazardous chemicals.

The no-rinse formula carefully removes soil residue and odor, leaving surfaces gleaming, streak-free, and looking like new. It is advisable to consult with a professional before using any cleaning product on marble surfaces.

To use the product, dilute it as necessary and mop the floor with a clean, lint-free, moist mop.

If soil remains persistent, adjust the dilution ratio or reapply the solution for optimal results. A sponge or scrubber is ideal for administering the solution.

Each gallon of Neutral pH Floor Cleaner can produce up to 128 gallons of cleaning solution, making it an economical and efficient choice for all your cleaning needs.


Uses a neutral pH solution

Compatible with hard floor cleaning equipment

Clean, citrus scent

Utilizable in toilets, sinks, and countertops

No-rinse formula


Not safe for carpets

Possible sticky residue

The Rocco & Roxie Supply Company

Rocco & Roxie Stain & Odor Eliminator for Strong Odor

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hardwood floors, hard surfaces, and carpeting

Rocco & Roxie Supply Co. offers a professional-grade cleaner that may be an excellent choice for pet owners looking for a high-quality product.

This bioenzymatic, natural product eliminates even the most stubborn stains and odors. Ammonia crystals in the solution decompose organic substances, ensuring that both the stain and odor are completely removed.

This product has been certified by the Carpet and Rug Institute as safe for use on all carpets, with no potential for color transfer.

Moreover, it is entirely safe to use around pets and children, and it can be applied to a variety of surfaces, including furniture, apparel, litter boxes, kennels, carriers, and laundry.

This product is pricier than other alternatives on the market, but it offers unmatched efficacy, eliminating stains and odors from any surface.

It is worth noting that this product may not deter your pet from returning to the same spot to defecate.

Certified delicate and safe, Rocco & Roxie’s cleaner contains no hazardous propellants and leaves no residue.

When in contact with odors and discoloration, the solution’s natural enzymes are activated, feeding on ammonia crystals and organic matter until they are completely eliminated.

This product is an Amazon best-seller with a 100% satisfaction guarantee for a reason. You will receive a full refund if your stains and odors persist after using the product.

Overall, Rocco & Roxie’s Supply Co. cleaner is a high-quality, secure, and effective option for pet owners seeking to eliminate stains and odors from their homes.


Natural, bio-enzymatic formula

Awarded certification by the Carpet & Rug Institute

Compatible with many surfaces and locations

Compatible for usage around children and animals



May not prevent future incidents in the same location

Simple Solution Stain & Odor Removal for Hardfloors

Simple Solution Hard Floor Pet Stain and Odor Remover

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  • Yes, stain remover
  • Odor Remover: Yes
  • Compatible with hardwood floors and hard surfaces

Hardfloors Stain & Odor Removal by Simple Solution is a dual-action solution that eliminates stains and odors from sealed hard surfaces, such as ceramic tile and other water-resistant floors.

The 32-ounce bottle has three different nozzle options, including stream, mist, and froth, making it a versatile choice for pet owners.

This pet stain and odor remover is expertly designed to eliminate urine, feces, vomit, and other common pet issues from both new and old problem areas.

The patented 3-in-1 nozzle sprayer provides users with additional options for eliminating stains and odors.

It is worth mentioning that this pet stain and odor remover is formulated to deter canines from urinating and defecating in the same spot in the future.

It is recommended for pet owners to perform a spot test before using this pet stain and odor remover on hardwood floors, as it may leave a residue.

The age of the stain may affect the product’s efficacy in removing both stains and odors, with odors being more easily removed.

Overall, Simple Solution’s Hardfloors Stain & Odor Removal is a dependable and efficient method for eradicating pet stains and odors from hard surfaces.

Its dual-action formula and versatile nozzle options make it essential for pet owners who want to maintain a clean and fragrant home.


Compatible with the majority of hard surfaces

3 spray choices

Prevents future collisions at the same location


Not suitable for carpets

Possible residue on hardwood flooring

Possibly ineffective for aged stains

How to Choose the Best Urine Cleaners for Your Dog

Why Does Dog Urine Smell?

Dog urine is composed of various components, including ammonia, bacteria, hormones, and uric acid.

As urine decomposes, the concentration of ammonia increases, and mercaptans are produced. Mercaptans are chemical compounds responsible for the long-lasting odor of skunk spray.

Uric acid crystals remain in the urine after it has dried. These crystals can be reactivated by moisture, including humidity. Dog urine serves as a scent marker for dogs.

This potent combination of components makes dog urine’s odor tenacious, even after the stain has dried, which is why specialized dog urine cleansers are essential.

When selecting a carpet cleaner to clean dog urine, there are several factors to consider.

Bio-Enzymatic Formulations

The presence of enzymes is necessary for effective cleansing of dog urine. These proteins break down the uric acid crystals and eliminate the odor-causing bacteria in the process.


While some dog urine cleaners for hardwood floors may be expensive, most are reasonably priced.

For those who operate kennels or foster dogs, purchasing a one-gallon size of the cleaner may be an additional cost-saving option.

Age of the Stain

Removing older stains can be more challenging, despite most cleaners’ claims that they work on both fresh and aged stains.

Using a UV blacklight to check for dog urine stains on a daily basis is a wise measure. This increases the chances of removing the stains permanently by catching them when they are brand new.


The potency of some fragrances may be overwhelming for some people. Visiting a pet store and sniffing various cleaners can help you decide whether or not you want a scented formula.

Spot Check

Performing a spot test is arguably the most important first step in using a product.

Although many products claim versatility, some formulas may leave residues. Conducting a spot test of the solution in a discreet location before application is crucial to avoid any floor damage.


1. What is the best cleaner to neutralize dog urine?

Combine equal parts of white vinegar and water. Use a sponge to apply the solution to the stain. After allowing it to remain for 5 to 10 minutes, wipe it down with a clean, dry towel.

Some experts recommend using a more diluted solution of 1/2 cup of vinegar to 1 gallon of warm water.

2. Does vinegar really work on dog urine?

Due to the acidic nature of vinegar, it will neutralize the bacteria in the dog’s urine, thereby eliminating the odor.

Vinegar is safe for pets, effective, inexpensive, and eco-friendly. Allow the vinegar solution to remain for 3 to 5 minutes, or follow the directions on the product label.

3. Will dog pee smell go away?

To prevent urine damage, quickly absorb dog urine with a damp cloth after urination. Soaking a cloth in a solution of detergent and warm water is a simple and effective way to clean up dog urine.

Clean the affected area with the cloth and ventilate the space by opening doors or windows for fresh air. The odor will disappear in a few minutes.

4. What can I mop my floor with to stop my dog from peeing on it?

Vinegar. Dogs have a similar distaste for the scent of vinegar as they do for citrus.

Due to their superior sense of smell and heightened sensitivity to odors, dogs exhibit an aversion to acidic aromas, including highly acidic vinegar.

The scent of vinegar has a greater repelling power on dogs than that of lemons and oranges, which is an important detail to remember.

5. Is hydrogen peroxide safe to use for cleaning dog urine?

Yes, hydrogen peroxide is a safe and effective cleaner for dog urine.

6. What kills the smell of dog urine?

Opt for Baking Soda. As a natural odor neutralizer, baking soda can effectively eliminate the odor of dog urine. Sprinkle it on the afflicted area, let it remain overnight, and then vacuum it to completely eliminate the odor.

7. Is it bad to clean urine with bleach?

Yes, cleaning urine with bleach is a bad idea because it can emit harmful gases that can irritate the eyes, nose, and throat.

8. How do you get dog urine smell out of tile?

Prepare a mixture of tepid water and vinegar, ensuring that you use the same quantity of each.

Then, pour the solution onto the floor and allow it to sit there for approximately 10 minutes. The vinegar will neutralize and eliminate the odor of the dog urine.


Hepper Advanced Bio-Enzyme Pet Stain and Odor Eliminator Spray is the best overall cleaner for dog urine on hardwood floors. It eliminates stains, leaves a neutral aroma, and does not require washing.

Additionally, this is the finest value! Oxy Fast Activated Pet Stain and Odor Remover utilizes oxygen cleaning properties, is safe for pets and children, and is reasonably priced.

BestForPets (bestforpets.org) would like to thank our visitors for choosing our website to read about and consult the best cleaners for dog urine.

We hope you have liked our evaluations of the best cleaners for dog urine on hardwood floors. These durable hardwoods are resistant to urine and stains.

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Dr. Barry Buttler

Dr. Barry Buttler, DVM, MS, DACVIM, is an experienced veterinarian who specializes in the care of small animals, specifically dogs. Dr. Barry K. Buttler is a member of the American Veterinary Medical Association and holds multiple certifications in small animal emergency medicine and geriatric pet health.

Veterinarian (DVM) Dr. Barry Buttler


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